Patient Journey Through Eligibility Checks and Prior Authorization: Wegovy and Zepound
GLP-1 medications like Wegovy and Zepbound are transforming weight loss treatment, but accessing them through insurance isn’t always easy. These drugs often require eligibility verification, prior authorization, and payer-specific documentation before they’re approved.
At Zappy Health, our team ensures every step of the process is streamlined — from verifying coverage to fighting denials. This guide walks through the exact workflow we follow for patients pursuing GLP-1 therapy, so nothing slips through the cracks.
Why Is Eligibility and Authorization So Important for GLP-1s?
High Rejection Rates: These medications are frequently denied on first submission due to strict insurer criteria.
Detailed Medical Necessity Requirements: Payers often require BMI history, previous failed therapies, and proof of comorbidities.
Significant Out-of-Pocket Risk: Patients need to know what’s covered — or not — before committing to treatment.
Time-Sensitive Shipping Windows: Once approved, pharmacies need quick coordination to prevent delivery delays.
By proactively managing this process, Zappy Health ensures more patients are approved faster, with fewer surprise costs.
How Zappy Health Handles the Process?

1. Intake and Initial Clinical Evaluation
Every patient starts with a digital intake that captures:
Height, weight, and BMI
Insurance information
Comorbid conditions (e.g., Type 2 diabetes, sleep apnea)
Prior attempts at weight loss
Consent for treatment and medication management
A Zappy provider reviews the intake, meets the patient via telehealth, and determines if Wegovy or Zepbound is clinically appropriate. If so, the provider documents the diagnosis (e.g., E66.01 – Morbid obesity) and initiates the medication request.
2. Insurance Eligibility Verification
Before requesting the medication, Zappy’s support team:
Checks formulary status via Availity or payer portals
Confirms whether prior authorization (PA) is required
Identifies step therapy rules or exclusions (e.g., must fail Saxenda or Contrave first)
Flags if the plan is Medicare (generally does not cover) or state Medicaid (coverage varies)
At this stage, patients are informed of any expected out-of-pocket costs or gaps in coverage.
3. Documentation Prep and Prior Authorization Submission
If PA is required (which it almost always is), Zappy assembles a complete submission including:
Recent clinical note with BMI and diagnosis
Weight history (including prior attempts at weight loss)
Evidence of lifestyle modification (e.g., notes from diet/exercise counseling)
Lab reports (e.g., HbA1c, lipid panels)
Letter of Medical Necessity from the prescribing provider
Each insurer has slightly different requirements. For example:
Aetna requires documentation of ≥5% weight loss after 3 months or prior program participation.
UHC demands lifestyle documentation and follow-up weight reduction for renewal.
Blue Cross expects comorbidity linkage if BMI is between 27–30.
Zappy ensures the right format, codes, and language for each payer.
4. Approval, Denial, or Appeal
Once submitted:
Most payers respond within 3–10 business days.
If approved, Zappy coordinates with a specialty pharmacy for fulfillment.
If denied, the team promptly initiates appeal protocols, including:
Updated documentation or lab results
Peer-to-peer review requests
Re-submission with expanded justification
Appeals are typically submitted within 30 days of denial, and patients are kept informed throughout.
What Zappy Verifies in the Process?
Active insurance status
Formulary inclusion for Wegovy/Zepbound
Step therapy or prior drug trial requirements
Medical necessity criteria (BMI, comorbidities)
Appeal deadlines and re-authorization timelines
How We Use Technology?
Zappy uses tools like:
Availity Essentials for real-time eligibility checks
EHR-PA integrations for faster submissions
Specialty pharmacy portals for shipment tracking
Automated alerts for reauthorization and expirations
All documentation is securely stored and referenced to avoid delays on renewals or appeals.

Communication With Patients
Zappy provides real-time updates at each step via:
Email summaries (after initial visit and after PA submission)
SMS updates (for approvals, denials, pharmacy shipments)
Calls (for appeals, rejections, or high-stakes changes)
Our care team ensures patients never feel left in the dark.
What Did We Learn?
Navigating insurance for Wegovy and Zepbound isn’t just paperwork — it’s a critical step to ensuring access to life-changing care.
At Zappy Health, our team:
Verifies insurance fast and accurately
Handles all documentation and authorization
Communicates clearly with patients
Manages appeals, renewals, and pharmacy coordination
What people are asking?